774: Fetal insulin resistance and maternal polycystic ovary syndrome

Insulin Resistance and Polycystic Ovary Syndrome.

BACKGROUND Insulin resistance and the associated compensatory hyperinsulinemia are common findings in women with PCOS, and may play a key role in this condition. METHODS In this article, we focused on the significance of insulin resistance in PCOS, reviewing the available literature on epidemiology, pathogenesis, pathophysiology and treatment of this condition. RESULTS It has been estimated...

Leptin, Ghrelin, Adiponectin, Homocysteine and Insulin Resistance Related to Polycystic Ovary Syndrome

The relationship between leptin, adiponectin, ghrelin, homocysteine, insulin resistance and other biochemical factors in women with polycystic ovary syndrome (PCOS) is controversial. We review how the expanded role of these factors in reproduction might impact our understanding of PCOS. For purposes of our review, we accessed the PUBMED database during the past 10 years. Our review confirms tha...

Calciotropic hormones, insulin resistance, and the polycystic ovary syndrome.

OBJECTIVE To investigate whether abnormalities in serum concentrations of 1,25-dihydroxyvitamin D [1,25(OH)(2)D], 25-hydroxyvitamin D [25(OH)D], parathyroid hormone (PTH), calcium, and phosphorus were associated with risk of polycystic ovary syndrome (PCOS) and obesity. The possible correlations of the calciotropic hormones with insulin resistance were also examined. DESIGN Case-control study...

Obesity and insulin resistance in women with polycystic ovary syndrome.

OBJECTIVE To evaluate the impact of obesity and various phenotypes of polycystic ovary syndrome (PCOS) on the insulin sensitivity index (ISI) and insulin resistance (IR). METHODS ISI and IR from 273 women in four phenotypes of PCOS and control groups were evaluated retrospectively. RESULTS The ISI and the percentage of IR were not significantly different among discrete phenotypes of PCOS gr...

Polycystic Ovary Syndrome: Insulin Resistance, Infertility, and Treatment